Metabolic Reverse Sleeve: Preliminary Results from the First 10 Cases

Area of Science:

• Bariatric surgery
• Minimally invasive procedures
• Gastrointestinal surgery

Background:

• Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass (RYGB) are effective but have long-term risks.
• Gastroesophageal reflux and marginal ulcers are known complications of current bariatric surgeries.
• The metabolic reversible sleeve (MRS) is a new, reversible bariatric procedure designed to preserve gastric anatomy.

Purpose of the Study:

• To evaluate the safety outcomes of the metabolic reversible sleeve (MRS) procedure.
• To report on the initial safety data from the first 10 consecutive patients undergoing MRS.
• To assess perioperative complications and early recovery associated with MRS.

Main Methods:

• Preoperative assessments included nutritional, psychiatric, and radiological evaluations.
• The MRS procedure involved laparoscopic gastric bipartition and jejunal bypass, preserving stomach anatomy.
• Standardized perioperative management and recording of safety outcomes (intraoperative complications, postoperative morbidity, readmissions) were employed.

Main Results:

• Ten patients (mean BMI 50.74 kg/m² ) underwent successful laparoscopic MRS without conversion.
• No intraoperative complications, anastomotic leaks, bleeding, or reoperations occurred.
• Patients were discharged between postoperative days 2-3 with normal lab values; mild nausea in 2 patients resolved spontaneously.

Conclusions:

• The metabolic reversible sleeve (MRS) appears to be a safe and feasible bariatric procedure in this initial series.
• No major perioperative complications were observed in the first 10 patients.
• Further research with larger cohorts and long-term follow-up is needed to confirm MRS safety and efficacy.