Virtual Human White Matter Dissection: A Stratigraphic Layer-by-Layer Dissection of Human Brain in Photogrammetry

Area of Science:

• Neurosurgery
• Medical Education
• 3D Modeling

Background:

• Understanding 3D neuroanatomy is crucial for neurosurgeons.
• Cadaveric dissection, the traditional learning method, is becoming less accessible.
• Existing 3D neuroanatomical models lack interactivity, limiting their educational utility.

Purpose of the Study:

• To develop an interactive, 3D photogrammetric model of white matter anatomy.
• To enable users to navigate and perform virtual stratigraphic dissections of white matter tracts.

Main Methods:

• Stepwise dissection of 12 human brain hemispheres using the Klingler technique.
• Photogrammetric capture of each dissection step.
• Processing, layering, labeling, and integration into a web-based 3D viewer.

Main Results:

• Creation of 10 lateral and 7 medial dissection models.
• Models were overlapped for stepwise exploration and annotation.
• A custom online 3D viewer was developed for computer-based interaction.

Conclusions:

• A high-resolution, interactive 3D photogrammetric model of white matter anatomy has been developed.
• This virtual dissection tool offers a realistic alternative to cadaver-based training.
• The tool can expand access to detailed neuroanatomical education globally.