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Updated: Feb 20, 2026

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
Published on: September 17, 2020
Circadian rhythms in aging and longevity: from molecular chronomics to translational gerontology
Anita Jagota1, Han Wang2, Yujiro Yamanaka3
1Neurobiology and Molecular Chronobiology Laboratory, Department of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, Telungana, 500046, India. ajsl@uohyd.ac.in.
Abstract:
Aging is accompanied by progressive deterioration in physiological homeostasis, increasing vulnerability to metabolic, neurodegenerative, cardiovascular, and immune disorders. Over the past two decades, circadian biology has emerged as a central integrative framework linking environmental time cues to cellular, tissue, and organismal resilience. The circadian timing system (CTS), composed of a central pacemaker in the suprachiasmatic nucleus (SCN) and peripheral clocks throughout the body, orchestrates daily rhythms in physiology and behavior. This special collection of articles in Biogerontology, entitled "Circadian Rhythms in Aging and Longevity," brings together 16 original and review articles from seven countries (India, China, Turkey, Brazil, Taiwan, Japan, and the USA). Collectively, these studies, span molecular chronomics, immune aging, neurodegenerative disease, metabolism and computational and translational perspectives, highlighting circadian regulation as a unifying principle in aging biology.
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