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Interactions Between Perioperative Anesthesia Management and Gut Microbiota: Current Research Advances
Naiqi Jiang1,2, Lei Wang3, Xiaodi Chen4
1School of Anesthesiology, Shandong Second Medical University, Weifang, 261053, China.
Cellular and Molecular Neurobiology
|February 18, 2026
Summary
The gut microbiota (GM) and anesthesia interact, potentially impacting health. This review explores anesthesia-induced GM imbalances and strategies for management to improve recovery.
Area of Science:
- Microbiology
- Anesthesiology
- Human Health
Background:
- The gut microbiota (GM) is crucial for human health.
- Dysbiosis is linked to inflammation, infection, and obesity.
- Anesthesia is vital for medical procedures.
Purpose of the Study:
- To review the interactions between perioperative anesthesia and the GM.
- To discuss mechanisms of anesthesia-induced dysbiosis.
- To propose management strategies for microbiota imbalances.
Main Methods:
- Literature review and synthesis of current knowledge.
- Analysis of potential mechanisms of anesthetic effects on GM.
- Identification of strategies for prevention and management.
Main Results:
- Anesthesia and GM exhibit bidirectional interactions.
- Anesthesia can induce gut microbiota dysbiosis.
- Strategies for managing dysbiosis are proposed.
Conclusions:
- Understanding anesthesia-GM interactions is key for patient health.
- Further research is needed on anesthetic modulation of GM.
- Microbiota-targeted interventions may optimize recovery.
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