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Updated: Feb 20, 2026

Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve
Published on: August 5, 2021
Multimodality imaging of pulmonary artery spindle cell sarcoma in Behçet's disease with cardiac valve involvement
Zhengyang Han1,2, Suyun Hou2, Wenrui Li2
1Department of Ultrasound medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Abstract:
Cardiac valve disease secondary to Behçet's disease complicated by pulmonary artery spindle cell sarcoma is extremely rare. We report a 59-year-old man with recurrent oral ulcers who presented with fever and chest pain. Laboratory findings and a positive pathergy test supported the diagnosis of Behçet's disease. Echocardiography showed severe tricuspid regurgitation and a pulmonary artery mass, which was corroborated by CT and cardiac MRI. PET/CT demonstrated hypermetabolic activity, and histopathology confirmed spindle cell sarcoma. This case underscores the pivotal role of multimodality imaging in the timely diagnosis of pulmonary artery spindle cell sarcoma associated with valvular involvement in Behçet's disease.
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