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A Case of Male Invasive Pleomorphic Lobular Breast Carcinoma

Kyla Manja1, Isabella Tondi Resta2, Samantha P Zuckerman1

  • 1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Journal of Breast Imaging
|February 18, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
invasive lobular carcinomamale breast cancerpleomorphic invasive lobular carcinoma

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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