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Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Infection01:20

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Healthcare Associated Infections II: Preventive Measures01:22

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
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Related Experiment Video

Updated: Feb 20, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
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Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

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Stillbirth and Infection.

Elizabeth M McClure1, Najia K Ghanchi2, Jean Kim1

  • 1Department of Social, Statistical, and Environmental Health Sciences, RTI International, Durham, NC, USA.

Clinics in Perinatology
|February 18, 2026
PubMed
Summary
This summary is machine-generated.

Infections cause 15% of stillbirths globally, with malaria and syphilis being the most significant contributors. Further research is needed to understand the impact of various infectious agents on stillbirth outcomes.

Keywords:
InfectionLow- and middle-income countriesStillbirth

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Perinatal Medicine

Background:

  • Stillbirth is a significant adverse pregnancy outcome, affecting approximately 2 million pregnancies annually worldwide.
  • Infectious agents are estimated to cause around 15% of all stillbirths.
  • While diverse pathogens like bacteria, viruses, fungi, and parasites can cause stillbirth, their specific contributions are often understudied.

Purpose of the Study:

  • To highlight the substantial impact of infectious agents on stillbirth.
  • To identify the infectious diseases most strongly associated with stillbirth globally.
  • To underscore the need for further investigation into the relationship between infections and stillbirth.

Main Methods:

  • This abstract is based on a review of existing literature and epidemiological data regarding stillbirth and infectious causes.
  • No new experimental or clinical data were generated for this summary.
  • The focus is on summarizing established knowledge and identifying key associations.

Main Results:

  • Infectious agents are a major cause of stillbirth, accounting for approximately 15% of cases.
  • Malaria and syphilis are identified as the infectious diseases with the strongest global association with stillbirth.
  • The quantitative relationship between many infections and stillbirth remains poorly understood.

Conclusions:

  • Infections represent a critical and preventable cause of stillbirth.
  • Global health strategies should prioritize the prevention and treatment of malaria and syphilis to reduce stillbirth rates.
  • Further research is essential to elucidate the mechanisms and prevalence of other infectious causes of stillbirth.