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Dual CD8 and TCR editing in regulatory T cells mediates HLA-A2-restricted tissue-specific homing

Raphaël Porret1, Fanny Lebreton2, Eleonora Pace3

  • 1Division of Immunology and Allergy, Lausanne University Hospital and University of Lausanne, 1005 Lausanne, Switzerland; Centre for Human Immunology Lausanne, 1005 Lausanne, Switzerland.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|February 19, 2026
PubMed

Keywords:
CD8 editingHLA-A2Treg therapyengineered TCRisletmigrationregulatory T celltolerancetype 1 diabetes

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