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Case Report: Thrombosed Mitral Leaflets in a Patient With Rheumatic Heart Disease: A Rare Clinical Case
Naser Khezerlou1, Mehdi Taghizadeh1, Mohammadjavad Sotoudeheian2
1Cardiovascular Research Center Tabriz University of Medical Science Tabriz Iran.
Clinical Case Reports
|February 19, 2026
Summary
Rheumatic heart disease can cause valve thrombus, leading to stroke. This case highlights how anticoagulation therapy effectively resolved mitral valve thrombus in an elderly patient.
Area of Science:
- Cardiology
- Neurology
- Internal Medicine
Background:
- Rheumatic heart disease is a major cause of cardiovascular disease.
- Valve thrombus formation is a serious complication.
- Stroke is a potential consequence of cardiac thrombus.
Purpose of the Study:
- To report a case of mitral valve thrombus in an 82-year-old male with rheumatic heart disease.
- To illustrate the diagnostic utility of transesophageal echocardiography (TEE).
- To highlight the therapeutic efficacy of anticoagulation therapy.
Main Methods:
- Case report of an 82-year-old male.
- Diagnostic imaging using transesophageal echocardiography (TEE).
- Treatment with anticoagulation therapy.
Main Results:
- TEE revealed a thrombus attached to the mitral valve leaflets (MVL).
- Anticoagulation therapy led to significant thrombus resolution.
- The patient presented with acute right-sided hemiplegia, suggesting a thromboembolic event.
Conclusions:
- Anticoagulation therapy can be effective in resolving mitral valve thrombus.
- Early diagnosis and treatment are crucial for managing complications of rheumatic heart disease.
- This case underscores the importance of considering valve thrombus in patients with stroke and underlying heart conditions.
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