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Evaluation of an Optimized Photobiomodulation Protocol for Accelerated Tooth Movement.

Anupama V Jain1, Shrinivas M Basavraddi1, Roopak Naik1

  • 1Orthodontics and Dentofacial Orthopedics, Shree Dharmastala Manjunathesawara College of Dental Sciences, Dharwad, IND.

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|February 19, 2026
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Summary

Photobiomodulation (PBM) therapy, when combined with orthodontic force, significantly accelerates maxillary tooth movement and extraction space closure by 40%. This pilot study suggests PBM can reduce orthodontic treatment time.

Keywords:
accelerated tooth movementdigital cast measurementsenmass space closurelow level laser therapy (lllt)nickel-titaniumorthodonticspbm protocolphotobiomodulation

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Area of Science:

  • Orthodontics
  • Biotechnology
  • Periodontology

Background:

  • Photobiomodulation (PBM) stimulates periodontal ligament cells, aiding bone remodeling.
  • PBM synergizes with orthodontic forces to potentially accelerate tooth movement and shorten treatment duration.

Purpose of the Study:

  • To compare the monthly rate of maxillary en-masse extraction-space closure over five months.
  • To evaluate the efficacy of PBM combined with standard orthodontic force versus standard force alone.

Main Methods:

  • A randomized, parallel-arm, single-blinded pilot study with control and PBM groups.
  • Standard orthodontic force (300g NiTi coil spring) applied after first bicuspid extraction.
  • PBM group received 810 nm diode laser irradiation four times monthly to anterior teeth.

Main Results:

  • The PBM group demonstrated a higher monthly rate of space closure (1.09mm/month) compared to the control group (0.7mm/month).
  • Tooth movement was 40% faster in patients receiving PBM.
  • The difference in monthly space closure rates was statistically significant (p<0.05).

Conclusions:

  • PBM, when added to orthodontic force, is associated with an increased monthly rate of extraction space closure.
  • The PBM protocol and methodology show promise for larger trials investigating accelerated tooth movement and reduced treatment times.