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Updated: Feb 20, 2026

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
Published on: May 31, 2024
Effect of Intracameral Air Bubble Injection on Early Visual and Intraocular Pressure Outcomes After
Gede Pardianto1, Stefenie Stefenie1, Givenchy A Winarjo1
1Ophthalmology and Vision Sciences, Universitas Prima Indonesia, Medan, IDN.
Purpose:
To evaluate the efficacy of intracameral air bubble injection in enhancing visual acuity following phacoemulsification cataract surgery.
Methods:
A prospective quasi-experimental study was conducted on 98 eyes from 78 participants who underwent phacoemulsification at SMEC Eye Hospital, Medan, between March and August 2025. All surgeries were performed by a single surgeon using the phaco-chop technique with bimanual irrigation/aspiration and intraocular lens (IOL) hydro-implantation using a Venturi phaco machine (Bausch+Lomb, Bridgewater, NJ, USA). At the conclusion of the surgery, 0.5% levofloxacin was administered intracamerally for infection prophylaxis, followed by air bubble injection. Postoperative outcomes included uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and intraocular pressure (IOP), analyzed using paired t-tests (95% CI; p<0.05).
Results:
UCVA improved significantly from logMAR 0.823 ± 0.113 (0.602-1.301) to 0.103 ± 0.073 (0.000-0.397) (p<0.001). BCVA improved from logMAR 0.651 ± 0.108 (0.477-0.903) to 0.083 ± 0.079 (0.000-0.176) (p<0.001). Mean IOP decreased from 17.23 ± 1.52 mmHg (16-20) to 13.26 ± 1.21 mmHg (11-16) (p<0.001). Minimal corneal edema and no significant inflammation were observed.
Conclusion:
Intracameral air bubble injection at the end of phacoemulsification significantly improves UCVA and BCVA, lowers IOP, and minimizes corneal edema. This simple, safe, and reproducible technique represents a valuable adjunct to cataract surgery for optimizing postoperative visual outcomes and patient satisfaction.
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