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Published on: May 25, 2022
Microbial Dysbiosis and Pathogenic Interplay in the Gut-Vaginal Axis: Implications for Polycystic Ovary Syndrome: A
Gokul Sudhakaran1, A R Sreekutty2, Ki Choon Choi3
1Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Abstract:
PCOS is the most common endocrine condition among reproductive-age women. This disorder causes irregular menstrual periods, increased hair growth, anovulation, and pregnancy difficulties. PCOS affects more than reproductive health. Recent PCOS research has focused on the Gut-Vaginal Axis, stressing the gut-vaginal microbiota reciprocal interaction. Modern society's ubiquitous stress affects hormonal activity. Stress-induced hormonal shifts may alter the vaginal and gut microbiomes These surroundings' microbial populations may contribute to PCOS-related systemic inflammation, insulin resistance, and reproductive difficulties. Stress hormones and microbiome abnormalities are linked with PCOS, but the mechanisms are yet unknown. This study examines how stress hormones affect gut and vaginal microbiomes in PCOS patients.
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