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Pediatric Myoepithelial Carcinoma of the Hand: A Case Report
Naomi Kelley1, Faye Oakes2, Lauren Nun1
1Department of Orthopedic Surgery, University of New Mexico School of Medicine, Albuquerque, New Mexico.
Case:
A 2-year-old boy with a painless volar left hand mass was diagnosed with myoepithelial carcinoma. Pathologic evaluation demonstrated positive S100 and cytokeratin AE1/AE3, negative glial fibrillary acidic protein (GFAP), and scarce epithelial membrane antigen (EMA)-positive cells. After tumor excision, the patient received 10 rounds of chemotherapy without radiation. He demonstrated no local recurrence approximately 3 years postoperatively; however, treatment is ongoing for metastatic disease.
Conclusion:
Myoepithelial carcinomas of the soft tissue are extremely rare, yet highly aggressive tumors with a tendency for local recurrence and metastasis. Timely diagnosis and treatment are a multidisciplinary challenge paramount for optimizing patient outcomes.
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