Related Experiment Video
Updated: Feb 21, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
[Bronchiectasis in adult: Radio-clinical features, etiologies and evolution]
Hamida Kwas1, Sabrine Majdoub Fehri1, Houiem Ben Kraiem1
1Department of Pneumology, University Hospital of Gabès, University of Sfax, Faculty of Medicine of Sfax. Tunisia.
Abstract:
Introduction-Aim: Bronchiectasis, which was once considered an orphan disease in developed countries, is common in Tunisia as in all emerging countries. The purpose of the present study is to determine radio-clinical features, etiologies and evolution of bronchiectasis.
Methods:
Monocentric, retrospective and descriptive study including all patients followed in the pulmonology department, Gabes University Hospital, for bronchiectasis confirmed by a chest CT scan between January 2016 and December 2023.
Results:
A total of 70 patients were included in the study. The mean age was 60.39±18.68 years. Symptomatology was dominated by cough and morning bronchorrhea. The diagnosis of bronchiectasis was confirmed in all patients. Chest CT scan showed diffused bronchiectasis in 85.7% cases, localized in 14.2% cases and bilateral in 87% cases. Bronchiectasis was secondary to pulmonary tuberculosis in 62.8% of cases and idiopathic in 12.8% of cases. Complications were dominated by bronchopulmonary infections (21.4% of cases) and hemoptysis (28.5% of cases). Ten patients (14.2%) with diffuse and bilateral bronchiectasis progressed to chronic respiratory failure.
Conclusion:
Our study shows that the etiologies of bronchiectasis are dominated in our context by tuberculosis despite the national tuberculosis control program. Diffuse and bilateral bronchiectasis are frequent and associated with a poor prognosis.
Related Concept Videos
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Pulmonary Cycle: Exhalation
Chronic Obstructive Pulmonary Disease-I: Introduction
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

