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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Cognitive Development During Adulthood01:30

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Web-Based Application for Cognitive and Functional Assessments in Dementia Screening: Mixed Methods, User-Centered

Nattaporn Piyaamornpan1,2,3, Suwat Srisuwannanukorn4, Kosit Tangthamrongthanawat5

  • 1Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Siriraj, Bangkok Noi, Bangkok, 10700, Thailand, 66 24197665, 66 24123009.

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Summary
This summary is machine-generated.

A new web application, Healthy Brain Test, shows strong validity and usability for dementia screening in older Thai adults. This digital tool facilitates accessible cognitive and functional assessments, aiding early detection and community-based care.

Keywords:
Alzheimer diseasecognitive screeningdementiafunctional assessmentneurocognitive disordersneuropsychologyweb application

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Area of Science:

  • Gerontology
  • Digital Health
  • Neuroscience

Background:

  • Rising dementia prevalence in Thailand necessitates accessible cognitive screening tools.
  • Limited availability of web-based cognitive assessments hinders early detection and community-based monitoring.
  • Ensuring usability and validity is crucial for implementing digital health solutions in real-world settings.

Purpose of the Study:

  • To develop and validate the Healthy Brain Test, a web application for cognitive and functional assessment in older Thai adults.
  • To design user-centered cognitive modules covering key cognitive domains for dementia screening.
  • To establish correlations between web-based assessments and clinical tools for determining diagnostic cutoffs.

Main Methods:

  • Developed Healthy Brain Test, a self-administered web application including digital Thai Mental State Examination (e-TMSE), clock drawing, verbal fluency, IQCODE-16, and IADLs.
  • Correlated web-based assessment results with traditional paper-based measures.
  • Utilized receiver operating characteristic (ROC) curves to determine diagnostic accuracy.

Main Results:

  • The e-TMSE demonstrated strong agreement with the traditional TMSE (r=0.837).
  • Significant correlations were found for verbal fluency, IQCODE-16, and IADL modules (P<.001).
  • The e-TMSE achieved an AUC of 0.84, with a cutoff ≤23 showing 88.6% sensitivity and 70.1% specificity for major neurocognitive disorder.

Conclusions:

  • Healthy Brain Test is a valid and usable web-based platform for dementia screening in older adults.
  • The application offers accessible, user-friendly remote evaluation for cognitive and functional status.
  • Further research should explore long-term feasibility and integration into clinical workflows for large-scale screening.