Related Experiment Video
Updated: Feb 21, 2026
12:00
Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
15.9K
Chronic total occlusion percutaneous coronary intervention: 2026 update
Semih Ceylan1, Deniz Mutlu2, Eleni Kladou3
1Bahcesehir University School of Medicine, Istanbul, Turkey.
The Journal of Invasive Cardiology
|February 19, 2026
Summary
Percutaneous coronary intervention for chronic total occlusion (CTO PCI) shows over 90% success in expert centers, with reduced symptoms and radiation exposure. New techniques and AI are enhancing outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Technology
Background:
- Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is a complex procedure with evolving strategies.
- Recent advancements in imaging, equipment, and techniques are improving CTO PCI outcomes.
- Understanding the latest developments is crucial for interventional cardiologists.
Purpose of the Study:
- To review and summarize the latest published literature on CTO PCI.
- To categorize recent advancements by procedural outcomes, techniques, and complications.
- To highlight ongoing studies shaping the future of CTO PCI.
Main Methods:
- Systematic review of published literature on CTO PCI from September 2023 to April 2025.
- Categorization of findings based on procedural success, novel techniques, complications, and emerging research.
- Analysis of multicenter data and ongoing randomized trials.
Main Results:
- Technical success rates exceeding 90% reported in expert centers.
- Significant long-term reductions in angina and dyspnea post-CTO PCI.
- Decreased radiation exposure due to equipment upgrades and operator awareness.
- Improved success and safety with techniques like coronary CT guidance, intravascular ultrasound, hydrodynamic recanalization, retrograde approaches, and AI tools.
Conclusions:
- CTO PCI is advancing rapidly, offering high success rates and improved patient outcomes.
- Technological innovations and refined techniques are key drivers of progress in CTO PCI.
- Ongoing research and large registries will further refine CTO PCI strategies and practice patterns.
Related Concept Videos
01:27Peripheral Artery Disease III: Interprofessional Care
388
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
388
01:27Coronary Artery Disease V: Interprofessional Care
320
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
320
01:28Acute Coronary Syndrome IV: Interprofessional Care
315
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
315
01:30Acute Coronary Syndrome III: Diagnostic Studies
312
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
312
01:23Peripheral Artery Disease V: Postoperative Nursing Management
431
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
431
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
487
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
487