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Updated: Jul 17, 2026
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Investigation of chikungunya arbovirus in cities of Bushehr province: An ELISA-based cross-sectional study
1Research Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Medical Entomology and Vector Control, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Background:
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus transmitted by Aedes aegypti and Aedes albopictus. Despite favorable ecological conditions in southern Iran, data on CHIKV exposure in Bushehr Province are lacking. This study aimed to determine the seroprevalence of CHIKV-specific IgG antibodies and assess potential viral circulation.
Methods:
A cross-sectional seroepidemiological survey was conducted from July to September 2023 in ten cities across Bushehr Province. Serum samples (n = 180) collected from volunteers at hospitals and blood donation centers were tested for CHIKV-specific IgG antibodies using a commercial ELISA kit.
Results:
Of the 180 serum samples analyzed, five tested positive for CHIKV IgG antibodies, yielding an overall seroprevalence rate of 2.78%. Seropositive individuals were identified in Bushehr, Dashtestan, and Dashti cities, indicating localized and possibly silent transmission.
Conclusions:
This study provides the first serological evidence of CHIKV exposure in Bushehr Province. The findings underscore the potential for local transmission in areas where competent Aedes vectors are present and highlight the urgent need for sustained vector surveillance, early warning systems, and public health preparedness in southern Iran.
