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2025 Clinical Practice Guidelines for the Management of Fontan Patients in Korea: A Consensus Statement With Graded
Min-Jung Cho1, Soo In Jeong2, Soo-Jin Kim3
1Department of Pediatrics, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Insights
Korean pediatric cardiology has improved complex congenital heart disease outcomes. New clinical practice guidelines offer tailored long-term management for Fontan circulation patients in Korea.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiovascular Surgery
Background:
- Significant advances in pediatric cardiology over 4 decades have improved prognosis for complex congenital heart diseases, including single ventricle physiology.
- An increasing number of patients with congenital heart disease are reaching adulthood, necessitating updated long-term management strategies.
- There is a specific need for clinical practice guidelines reflecting current medical trends for Fontan circulation patients.
Purpose of the Study:
- To establish the first Korean clinical practice guidelines for the long-term management of Fontan patients.
- To address the growing need for updated guidelines reflecting the latest medical trends in pediatric cardiology.
- To provide a framework for managing the increasing adult population with Fontan circulation.
Main Methods:
- Formation of a Korean Fontan cohort in 2019 and a guideline development committee in 2023.
- Review and discussion of methodology and content by 19 working committee members with expert consultation.
- Incorporation of international guidelines (US, Europe, Australia), Korean-specific data, survey data from the Korean Pediatric Cardiology Society, and meta-analysis results.
Main Results:
- Development of the first Korean clinical practice guidelines for Fontan patients.
- Inclusion of evaluations of international clinical guidelines.
- Proposal of outpatient follow-up schedules specifically tailored to the Korean clinical context.
- Rigorous review by leading national experts to ensure completeness and applicability.
Conclusions:
- The newly developed Korean clinical practice guidelines provide comprehensive, context-specific recommendations for Fontan patient management.
- These guidelines reflect the latest advancements in pediatric cardiology and address the unique needs of the Korean healthcare system.
- The guidelines aim to enhance the long-term care and outcomes for adult Fontan circulation patients in Korea.
Abstract:
Over the past 4 decades, significant advances in pediatric cardiology in Korea have led to marked improvements in the prognosis of patients with complex congenital heart diseases, including single ventricle physiology. The number of patients reaching adulthood has steadily increased. In particular, there is a growing need for clinical practice guidelines that reflect the latest medical trends for the long-term management of Fontan circulation patients. Accordingly, a Korean Fontan cohort was established in 2019, and a guideline development committee was formed in 2023 to publish the first Korean clinical practice guidelines for Fontan patients. Nineteen working committee members discussed and reviewed the methodology and content with expert consultation, incorporating both international guidelines and Korean-specific data. Through multiple rounds of review and discussion between authors and editors, the content was finalized, including evaluations of clinical guidelines from the United States, Europe, and Australia. The guidelines also incorporate survey data from members of the Korean Pediatric Cardiology Society and results from meta-analyses, and propose outpatient follow-up schedules tailored to the Korean clinical context. The finalized guidelines underwent rigorous review by leading national experts to enhance their completeness and applicability.
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