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Updated: Jun 5, 2026

A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri)
Published on: April 11, 2018
The DNA methylation landscape of naturally short-lived killifish
Mara Steiger1,2, Nishita Singh1, Alexandra M Tyers3
1Max Planck Institute for Molecular Genetics, Berlin, Germany.
Abstract:
Annual killifish of the genus Nothobranchius are naturally short-lived vertebrates that exhibit a wide range of aging characteristics typically observed in mammals. Here, we provide the first comprehensive whole-genome methylation map for two species, revealing local age-related as well as tissue-specific dynamics in the DNA methylome. Our maps and results support the annual killifish as a model organism and further highlight its value for studying aging including possible health status predictions in vertebrates.
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