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A cGMP-applicable Expansion Method for Aggregates of Human Neural Stem and Progenitor Cells Derived From Pluripotent Stem Cells or Fetal Brain Tissue
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Bioreactor expansion of human neural progenitor cells for exosome scalable production and miRNA-engineering

Miriam Corraliza-Gomez1,2, Marta Ianni1,3, Diogo E S Nogueira4,5

  • 1Neuroinflammation Signaling and Neuroregeneration, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.

Journal of Biological Engineering
|February 20, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Cell-free therapiesNeural precursor cellsParacrine signalingStirred-tank bioreactorsUpscaled-exosome productionVertical-wheel bioreactorsmiRNA-124-engineered exosomes

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