Related Experiment Video
Updated: May 16, 2026

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
Published on: October 24, 2017
Roughness-induced diffusion enhancement in asymmetric potentials under nonequilibrium fluctuations
Li-Ming Fan1, Ming-Gen Li2, Tian-Fu Gao1
1Shenyang Normal University, College of Physical Science and Technology, Shenyang 110034, People's Republic of China.
None:
Roughness in a potential landscape is canonically understood as a kinetic impediment that invariably suppresses the diffusion of thermally driven particles, particularly in the absence of an external bias. Here we reveal a contrasting principle for systems driven by nonequilibrium fluctuations. Focusing on a paradigmatic model of such fluctuations, such as Poisson shot noise, we demonstrate that for driven particles, roughness on an asymmetric potential can act as an effective means to accelerate diffusion. In a specific regime, the effective diffusion coefficient exhibits a pronounced enhancement, culminating in a peak value that unambiguously surpasses the benchmark value set by free-particle diffusion. This phenomenon originates from a microscopic mechanism we term unidirectional slide inhibition: A synergy between the potential's global asymmetry and its local roughness selectively arrests the particle's backward slide on the gentler slope. This selective arrest acts as a ratchet, enhancing the efficiency of forward barrier crossings. This process simultaneously boosts net transport and magnifies displacement variance by promoting successful, long-range forward jumps over backward slides. Our findings establish a new principle for nonequilibrium control, demonstrating that potential roughness can be harnessed to dramatically enhance diffusion, opening avenues for novel particle separation technologies and offering a new framework for understanding transport in biological and soft-matter systems where such rugged energy landscapes are ubiquitous.
More Related Videos
11:33All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
Published on: January 19, 2018
05:56Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells
Published on: November 12, 2020
Related Concept Videos
Diffusion
Diffusion
Carrier Transport
Drift Current:
The drift of charge carriers is started by an external electric field (E). Charged particles, such as electrons and holes, experience an acceleration between collisions with lattice atoms. For electrons, this results in a drift velocity (vd) given by:
Debye–Huckel–Onsager Conductance Equation
Electrochemical Systems
Processes at Electrodes