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A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
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Cytomegalovirus Lymphadenitis Mimicking Relapsed Lymphoma After CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy

Lubna Osman-Kardash1, Jay Spiegel2, Antonio M Jimenez Jimenez2

  • 1Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
|February 20, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
CAR T cell therapycytomegaloviruslymphadenitislymphoma

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

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