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CDK9 interacts with a RanGTP-importin-β complex to regulate erythroid enucleation

Lucas M Newton1,2,3,4,5, Krystle Y B Lim1,2, Donia Y Abeid1,2

  • 1Department of Biochemistry & Chemistry, La Trobe University, Melbourne, VIC 3073, Australia.

Journal of Cell Science
|February 20, 2026
PubMed
Summary

Cyclin-dependent kinase 9 (CDK9) interacts with the importin-beta complex during red blood cell formation. This interaction is crucial for the final nuclear extrusion step in erythroid enucleation.

Keywords:
CDK9EnucleationErythropoiesisImportin-β

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