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Updated: Feb 21, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Comparison of methods for inframammary fold fixation of deep inferior epigastric perforator flap breast
Tomohiro Kojimahara1, Hiroki Mori1, Sayuri Kato1
1Plastic and Reconstructive Surgery, Institute of Science Tokyo, Tokyo, Japan.
Background:
Various methods for inframammary fold (IMF) fixation in deep inferior epigastric artery perforator (DIEP) flap breast reconstruction have been reported. This quantitative study focused on the comparison of IMF fixation results between immediate one-stage (internal fixation), delayed one-stage (de-epithelialized method), and two-stage (capsule fixation) reconstruction.
Methods:
A retrospective study of 34 patients who underwent unilateral DIEP flap reconstruction was conducted. The IMF height, grouped by reconstruction methods, was measured from the standardized clinical photographs >6 months after the DIEP flap reconstruction (post-DIEP) and >6 months after the flap revision surgery (final), and compared with the healthy side.
Results:
In the order of immediate one-stage, delayed one-stage, and two-stage reconstruction, respectively, the average (± standard deviation) post-DIEP IMF heights were -1.60 ± 0.65 cm, -0.19 ± 1.16 cm, and -1.40 ± 1.11 cm, and the average final IMF heights were -1.20 ± 0.44 cm, -0.19 ± 0.52 cm, and -0.68 ± 0.98 cm.
Conclusion:
After DIEP flap breast reconstruction, the IMF of the reconstructed side tends to be lower than the healthy side. The de-epithelialized method used in delayed one-stage reconstruction showed relatively good IMF fixation after DIEP flap reconstruction compared with other reconstruction methods. By performing additional IMF procedures during flap revision surgery, the average IMF height ranged from -1.2 to -0.19 cm compared with the healthy side.

