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Identifying high healthcare utilizers following cervical spine surgery using comprehensive predictive modeling
Rushmin Khazanchi1, Divy Kumar1, Rishi Jain1
1Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Journal of Craniovertebral Junction & Spine
|February 20, 2026
Summary
Machine learning models can predict high healthcare utilization after cervical spine fusion surgery. Key predictors include operating room duration and preoperative use of neuromodulators and opioids.
Area of Science:
- Spine Surgery
- Health Services Research
- Machine Learning in Healthcare
Background:
- Rising healthcare expenditures for chronic spinal conditions and surgery necessitate predictive models.
- Identifying patients at high risk for postoperative healthcare utilization is crucial for resource allocation and care optimization.
Purpose of the Study:
- To develop machine learning (ML) models for predicting postoperative healthcare utilization in cervical spine fusion patients.
- To leverage comprehensive preoperative patient data, including medical, surgical, and social histories, for granular prediction.
Main Methods:
- Analysis of a cohort of 4480 anterior and posterior cervical decompression and fusion surgeries (2002-2022).
- Systematic extraction of patient and operative characteristics.
- Application and optimization of various ML algorithms to predict high healthcare utilizers within 90 days post-surgery.
- Computation of SHAP feature importance for the top-performing model.
Main Results:
- 12% of patients were identified as high healthcare utilizers.
- All ML models surpassed the American Society of Anesthesia benchmark.
- The Balanced Random Forest model achieved the highest discriminative performance (AUC: 0.772 ± 0.007).
- Top predictive features included increased operating room duration, and 90-day preoperative neuromodulator and opioid usage.
Conclusions:
- Successfully developed prognostic ML models to predict high healthcare utilization within 90 days of cervical spine surgery.
- These validated models show potential to assist spine surgeons in clinical workflows.
- Accurate prediction aids in optimizing patient care and managing healthcare resources effectively.
