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An open-source JavaScript clinical neurophysiology library for education and clinical research.

Sampsa Lohi1,2,3, Petro Julkunen2,4, Reetta Kälviäinen3,5

  • 1Department of Clinical Neurophysiology, North Karelia Central Hospital, Joensuu, Finland.

Clinical Neurophysiology Practice
|February 20, 2026
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Summary

Epicurrents is a new JavaScript library for processing neurophysiological data in web browsers. This open-source tool enhances clinical neurophysiology education and research accessibility.

Keywords:
Clinical neurophysiologyElectroencephalographyElectromyographyNerve conduction studiesOpen sourceWeb application

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Area of Science:

  • Neurophysiology
  • Web Technologies
  • Scientific Software Development

Background:

  • Clinical neurophysiology generates complex data requiring specialized processing and visualization tools.
  • Existing tools may lack accessibility, cross-platform compatibility, or ease of integration for educational and research purposes.

Purpose of the Study:

  • To introduce Epicurrents, an open-source JavaScript library designed for processing and displaying neurophysiological signal data.
  • To provide a modular, web-based solution that supports multiple neurophysiological modalities and open data standards.

Main Methods:

  • Developed a modular JavaScript library with support for European Data Format (EDF) and Digital Imaging and Communications in Medicine (DICOM).
  • Integrated optional Python and Open Neural Network Exchange (ONNX) for advanced signal processing.
  • Implemented a progressive web application architecture for online/offline use, requiring no installation.

Main Results:

  • Epicurrents demonstrated successful application in educational settings, including use by the European Academy of Neurology for electroencephalography (EEG) education.
  • Architectural optimizations like shared memory buffers and asynchronous processing mitigated JavaScript's memory management limitations for large datasets.
  • The library proved effective for hands-on learning and collaborative research.

Conclusions:

  • Epicurrents is the first modular JavaScript library for clinical neurophysiology education.
  • Web technologies, exemplified by Epicurrents, can significantly enhance collaborative scientific research in neurophysiology.
  • While not for clinical diagnostics, its accessibility and extensibility make it valuable for education and research.