Isolated coronary artery bypass in octogenarians: does gender matter?

Area of Science:

• Cardiovascular Surgery
• Geriatric Medicine
• Clinical Outcomes Research

Background:

• Coronary artery bypass grafting (CABG) is increasingly performed in octogenarians due to longer life expectancy.
• Coronary artery disease (CAD) burden is rising in the elderly population, necessitating advanced surgical interventions.

Purpose of the Study:

• To investigate sex-specific differences in perioperative characteristics and early outcomes.
• To evaluate the safety and efficacy of CABG in octogenarian patients stratified by gender.

Main Methods:

• Retrospective analysis of 104 patients aged ≥80 years undergoing isolated CABG (2017-2023).
• Patients were stratified by gender, comparing preoperative comorbidities, intraoperative variables, and postoperative outcomes.
• Primary endpoint: in-hospital mortality.

Main Results:

• Males had larger body surface area and longer ICU stays; females had more frequent CABG x5.
• Males showed higher prevalence of chronic obstructive pulmonary disease (COPD) and smoking.
• Overall in-hospital mortality was low (3.8%) and did not differ significantly between genders.

Conclusions:

• CABG in octogenarians is associated with low early mortality and acceptable complication rates irrespective of gender.
• Observed preoperative and intraoperative gender-based differences can guide individualized perioperative management strategies for this demographic.