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Related Experiment Video

Updated: Feb 22, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
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Association Between Physical Activity, Sedentary Behavior and Breast Cancer Risk Among Moroccan Women: A Multicenter

Siham Mrah1, Najoua Lamchabbek2,3, Mounia Amzerin1

  • 1Laboratory Research of Cancer and Chronic Diseases, Faculty of Medicine and Pharmacy of Tangier, Abdelmalek Essaadi University, Tetouan 93000, Morocco.

Epidemiologia (Basel, Switzerland)
|February 20, 2026
PubMed
Summary

Regular physical activity, including moderate exercise and active daily habits like walking, significantly lowers breast cancer risk in Moroccan women. Higher activity levels are associated with substantially reduced odds of developing the disease.

Keywords:
breast cancercase–control studyoccupational activityphysical activitysedentary behavior

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Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Breast cancer incidence is rising in North Africa, with limited data on lifestyle factors.
  • Understanding modifiable risk factors is crucial for regional breast cancer prevention strategies.

Purpose of the Study:

  • To investigate the link between physical activity, sedentary behavior, work habits, and breast cancer risk in Moroccan women.
  • To address a critical data gap in North African breast cancer epidemiology.

Main Methods:

  • A case-control study involving 1400 breast cancer cases and 1400 matched controls (2019-2023).
  • Comprehensive assessment of physical activity across the lifespan (type, intensity, duration).
  • Statistical analysis using adjusted odds ratios (aORs) and 95% confidence intervals (CIs).

Main Results:

  • Moderate physical activity showed a significant inverse dose-response relationship with breast cancer risk.
  • Highest quartile of physical activity was associated with substantially lower breast cancer odds (aOR = 0.37).
  • Active daily habits (walking, stair climbing) reduced risk, while occupational fatigue and sweating increased it.

Conclusions:

  • Physical activity is a key factor in reducing breast cancer risk among Moroccan women.
  • Moderate activity and active daily routines like brisk walking are protective.
  • While findings support physical activity for prevention, the study's retrospective design limits causal conclusions.