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Should lamotrigine be discontinued before TMS treatment: A report of three cases

Xia Li1, Ethan Li1, Cory Weissman1

  • 1Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|February 20, 2026
PubMed
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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.