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Updated: Feb 22, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING

Ryuichi Takahashi1, Zhikuan Zhang1, Akiko Fujimura1

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Structure (London, England : 1993)
|February 20, 2026
PubMed

Keywords:
IFI16STINGcryo-EMinflammasomepyrin domain

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