Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.7K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.7K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.2K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.2K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

560
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
560
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.1K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.1K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

663
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
663
Longitudinal Research02:20

Longitudinal Research

13.5K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Factors associated with tuberculosis symptom reporting among persons deprived of liberty in Brazil during active case finding: a cross-sectional study.

BMJ public health·2026
Same author

Comparison of phylogenetic metrics of transmission between symptomatic and asymptomatic tuberculosis in individuals who were incarcerated in Brazil in 2008-24: a retrospective genomic epidemiology study.

The Lancet. Microbe·2026
Same author

Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study.

PLoS medicine·2026
Same author

Interferon gamma release assay and sputum GeneXpert positivity for tuberculosis burden detection in people deprived of liberty in Brazil: a cross-sectional study.

BMC public health·2026
Same author

Distinguishing Relapse from Reinfection in Recurrent Tuberculosis: A Genomic and Epidemiologic Study in Brazil.

medRxiv : the preprint server for health sciences·2026
Same author

Challenges and Opportunities for Improved Tuberculosis and HIV Prevention in South America.

Open forum infectious diseases·2026

Related Experiment Video

Updated: Feb 22, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.7K

Longitudinal symptom transitions predict incident tuberculosis risk in serial active case finding.

Esther Jung1, José Victor Bortolotto Bampi2, Alessandra Moura da Silva2

  • 1Stanford University School of Medicine, Stanford, California, United States.

The Journal of Infectious Diseases
|February 20, 2026
PubMed
Summary

Monitoring symptoms over time can improve tuberculosis (TB) screening in high-risk groups. Developing new symptoms, especially with prior chest imaging abnormalities, significantly increases TB risk.

Keywords:
active case findingasymptomaticprisonsscreeningtuberculosis

More Related Videos

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

19.3K
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

14.9K

Related Experiment Videos

Last Updated: Feb 22, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.7K
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

19.3K
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

14.9K

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Clinical Screening

Background:

  • Tuberculosis (TB) screening commonly uses single-time point symptom checks.
  • There is a need to evaluate more dynamic approaches for TB detection.

Purpose of the Study:

  • To assess the added value of longitudinal symptom monitoring for TB screening.
  • To identify specific symptom patterns associated with incident TB in a high-risk population.

Main Methods:

  • A prospective cohort study was conducted with 2,282 incarcerated men in Brazil.
  • Participants underwent symptom assessments and TB testing (Xpert/culture) every four months.
  • Statistical analysis included adjusted risk ratios (aRR) to compare TB risk based on symptom status.

Main Results:

  • Developing new symptoms was linked to a 2.31-fold increased risk of TB.
  • This association was strongest (aRR 2.49) in individuals with prior radiographic abnormalities.
  • Persistently symptomatic individuals did not show a significant association with incident TB (aRR 1.27).

Conclusions:

  • Longitudinal symptom monitoring can enhance TB screening effectiveness in correctional settings.
  • Combining symptom tracking with radiography may further improve early TB detection in vulnerable populations.