Multimodal treatment approach for giant condylomata acuminata complicated by lichen sclerosus: A case report
Lunhui Chang1, Xiaofei Sun2, Dekun Song2
1The First Hospital of Anhui University of Science and Technology, Huainan 232007, China; Department of Phototherapy, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China; Skin Cancer Center, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China; Institute of Photomedicine, School of Medicine, Tongji University, Shanghai 200443, China.
Abstract:
A 65-year-old male presented with cauliflower-like growths on the penis for two years. Physical examination revealed erythema and cutaneous atrophy on the prepuce, glans, and external urethral meatus, with diffuse cauliflower-like proliferations on this basis. Based on the clinical and histopathological findings, a diagnosis of condylomata acuminata (CA) with concomitant lichen sclerosus (LS) was made. The patient received a multimodal treatment involving 5-aminolevulinic acid photodynamic therapy (ALA-PDT), Holmium-laser, and curettage, which led to significant improvement of the lesions. No recurrence was observed during a 4-year follow-up period.
