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Updated: Feb 22, 2026

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Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
Published on: May 27, 2016
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Phytophotodermatitis: An under-recognized diagnostic pitfall in chemical burns.
Summary
Phytophotodermatitis, a skin reaction from plant compounds and UV light, mimics burns. Prompt diagnosis via history and symptomatic treatment with corticosteroids leads to rapid healing, though hyperpigmentation may persist.
Area of Science:
- Dermatology
- Toxicology
- Plant Science
Background:
- Phytophotodermatitis is a rare chemical burn mimic caused by plant photosensitizers and UV exposure.
- Clinical presentation resembles second-degree burns, complicating diagnosis.
- Diagnosis relies on identifying the sequence of phototoxic plant contact followed by UV radiation.
Purpose of the Study:
- Report five cases of phytophotodermatitis.
- Provide an overview of phytophotodermatitis diagnosis and management.
Main Methods:
- Retrospective case series of five patients managed in Plastic Surgery.
- Data collection included demographics, diagnosis time, etiology, treatment duration, and complications.
Main Results:
- Implicated plant families: Apiaceae, Moraceae, Rutaceae.
- Mean symptom onset at 28.8 hours; presentations included erythema, vesicles, and bullae.
- All patients treated with water irrigation and topical corticosteroids; none required surgery. One case had post-inflammatory hyperpigmentation.
Conclusions:
- Thorough patient history is crucial for prompt diagnosis and treatment.
- Management involves analgesics and topical corticosteroids, typically resulting in rapid healing.
- Potential long-term sequela includes persistent cutaneous hyperpigmentation.
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