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Related Concept Videos

Burn Injuries01:22

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
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Drug Toxicity: Allergic Reactions01:30

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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
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Flame Photometry: Overview01:02

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Flame photometry, also known as flame emission spectrometry, is a technique used for the qualitative and quantitative analysis of elements present in a sample using a flame as the source of excitation energy. The concept of flame photometry was realized in the early 1860s by Kirchhoff and Bunsen, who discovered that specific elements emit characteristic radiation when excited in flames. The first instrument developed for this purpose was used to measure sodium (Na) in plant ash using a Bunsen...
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In a flame photometer, when a solution like potassium chloride is aspirated into the flame, the solvent evaporates, leaving behind dehydrated salt. This salt dissociates into free gaseous atoms in their ground state. Some of these atoms absorb energy from the flame, leading to their excitation. The excited atoms return to the ground state, emitting photons at characteristic wavelengths. Because only electronic transitions are involved, the resulting emission lines are very narrow. The intensity...
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Toxic Reactions: Overview01:26

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Phytophotodermatitis: An under-recognized diagnostic pitfall in chemical burns.

G Lacroix1, Q Samaran2, C Herlin1

  • 1Plastic and Reconstructive Surgery Unit and Burn Unit, Lapeyronie Hospital, University Hospital of Montpellier, 34025 Montpellier, France.

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|February 20, 2026
PubMed
Summary

Phytophotodermatitis, a skin reaction from plant compounds and UV light, mimics burns. Prompt diagnosis via history and symptomatic treatment with corticosteroids leads to rapid healing, though hyperpigmentation may persist.

Keywords:
Brûlures chimiquesChemical burnPhototoxicityPhototoxicitéPhytophotodermatitisPhytophotodermatoses

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Area of Science:

  • Dermatology
  • Toxicology
  • Plant Science

Background:

  • Phytophotodermatitis is a rare chemical burn mimic caused by plant photosensitizers and UV exposure.
  • Clinical presentation resembles second-degree burns, complicating diagnosis.
  • Diagnosis relies on identifying the sequence of phototoxic plant contact followed by UV radiation.

Purpose of the Study:

  • Report five cases of phytophotodermatitis.
  • Provide an overview of phytophotodermatitis diagnosis and management.

Main Methods:

  • Retrospective case series of five patients managed in Plastic Surgery.
  • Data collection included demographics, diagnosis time, etiology, treatment duration, and complications.

Main Results:

  • Implicated plant families: Apiaceae, Moraceae, Rutaceae.
  • Mean symptom onset at 28.8 hours; presentations included erythema, vesicles, and bullae.
  • All patients treated with water irrigation and topical corticosteroids; none required surgery. One case had post-inflammatory hyperpigmentation.

Conclusions:

  • Thorough patient history is crucial for prompt diagnosis and treatment.
  • Management involves analgesics and topical corticosteroids, typically resulting in rapid healing.
  • Potential long-term sequela includes persistent cutaneous hyperpigmentation.