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Establishment and Validation of a Standardized Midface Assessment Protocol Using Three-Dimensional

Wenqian Yang1,2, Yuyan Yang1, Yarong Chi1

  • 1Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No.1, Shuaifuyuan, Dongcheng District, Beijing, 100005, China.

Aesthetic Plastic Surgery
|February 20, 2026
PubMed
Summary
This summary is machine-generated.

A new standardized 3D stereophotogrammetry protocol for midface anthropometry was developed and validated. This reliable method enhances facial morphology assessment and surgical planning in clinical settings.

Keywords:
MidfaceProtocol establishmentReliabilityThree-dimensional stereophotogrammetry

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Area of Science:

  • Anthropometry
  • 3D Imaging
  • Facial Analysis

Background:

  • Three-dimensional (3D) stereophotogrammetry is crucial in anthropometry for clinical and aesthetic applications.
  • A standardized 3D protocol for midface assessment was lacking.
  • This study aimed to create and validate such a protocol.

Purpose of the Study:

  • To develop a standardized 3D anthropometric protocol for the midface region.
  • To assess the reliability and reproducibility of the developed protocol.

Main Methods:

  • Twenty-eight female and nine male participants (74 midfaces) were included.
  • Two sets of 3D facial images were acquired per participant.
  • 34 anatomical landmarks defined 13 midface zones for 36 measurements (surface area, volumetric, angular, linear).

Main Results:

  • The protocol demonstrated high reliability across all assessments.
  • Low measurement error and excellent agreement were observed.
  • Intraclass correlation coefficients consistently exceeded 0.95, indicating strong reproducibility.

Conclusions:

  • The developed 3D stereophotogrammetry protocol is reliable and reproducible for midface anthropometric evaluation.
  • This protocol can be applied in clinical settings for facial morphology assessment, surgical planning, and outcome evaluation.