Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

863
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
863
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

4.8K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
4.8K
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

752
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
752
Pleura of the Lungs01:13

Pleura of the Lungs

8.1K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
8.1K
Pneumothorax-II01:27

Pneumothorax-II

1.1K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transfer Learning in Convolutional Neural Network to Differentiate Follicular Adenoma Versus Follicular Carcinoma of Thyroid on Aspiration Cytology Material.

Cytopathology : official journal of the British Society for Clinical Cytology·2026
Same author

Cytological Diagnosis of Metastatic Dedifferentiated Chondrosarcoma in Pleural Effusion: A Rare Case Report.

Diagnostic cytopathology·2026
Same author

Diagnosis of Amoebic Peritonitis in Peritoneal Fluid in a Patient With Acute Intestinal Obstruction: A Case Report.

Diagnostic cytopathology·2026
Same author

Metastatic Papillary Thyroid Carcinoma in Pleural Effusion: Diagnostic Challenges in Effusion Cytology.

Cytopathology : official journal of the British Society for Clinical Cytology·2026
Same author

Comparative Evaluation of Transfer Learning Models for Detecting Malignant Cells in Urinary Cytology.

Cytopathology : official journal of the British Society for Clinical Cytology·2026
Same author

Diagnostic Dilemma in a Lymph Node Aspiration Cytology.

Cytopathology : official journal of the British Society for Clinical Cytology·2026

Related Experiment Video

Updated: Feb 22, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

2.3K

Myelomatous Pleural Effusion: A Case Report.

Kinjal Patel1, Natasha Modi1, Avinash Munshi1

  • 1National Institute of Medical Sciences, Jaipur, Rajasthan, India.

Diagnostic Cytopathology
|February 20, 2026
PubMed
Summary

A rare case of myelomatous pleural effusion in multiple myeloma is presented. Early identification of this aggressive complication is crucial for tailored treatment and improved patient outcomes.

Keywords:
Plasmablastmyelomapleural effusion

More Related Videos

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

1.6K
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.3K

Related Experiment Videos

Last Updated: Feb 22, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

2.3K
Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

1.6K
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.3K

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Multiple myeloma is a common blood cancer.
  • Serous cavity effusions are rare in multiple myeloma, often indicating advanced disease.

Purpose of the Study:

  • To report a rare case of leukemic transformation with myelomatous pleural effusion in a multiple myeloma patient.
  • To highlight the importance of recognizing this aggressive complication.

Main Methods:

  • Case report of a 50-year-old patient with multiple myeloma.
  • Clinical presentation: dyspnea, cough, fatigue.
  • Diagnostic tools: cross-sectional imaging, cytopathologic examination of pleural fluid.

Main Results:

  • Massive pleural effusion with partial pulmonary collapse.
  • Cytopathology confirmed atypical plasma cells and plasmablasts, indicative of myelomatous effusion.
  • Leukemic transformation concurrent with pleural infiltration.

Conclusions:

  • Myelomatous effusions, though rare, signify an aggressive disease variant.
  • Requires specific therapeutic strategies distinct from common effusions.
  • Emphasizes clinical vigilance and prompt cytologic evaluation for unexplained effusions in multiple myeloma patients.