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The CoDe/ETHIC-Talk: A theory-informed intervention to support ethical deprescribing in hospice care
Tahani Alwidyan1, Omar Shamieh2, Bayan Al-Talla3
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, Jordan.
Research in Social & Administrative Pharmacy : RSAP
|February 21, 2026
Summary
This study developed a new framework to improve medication deprescribing in hospice care by combining ethical reasoning with empathetic communication, addressing patient emotional readiness and clinical challenges.
Area of Science:
- Gerontology
- Palliative Care
- Health Services Research
Background:
- Polypharmacy is prevalent in hospice settings, increasing patient burden and misaligning care goals.
- Current deprescribing practices in hospice are inconsistent and lack ethical responsiveness, especially concerning emotional readiness.
Purpose of the Study:
- To develop a theory-informed framework for deprescribing in hospice care.
- The framework integrates ethical reasoning and emotionally intelligent communication.
Main Methods:
- Semi-structured interviews were conducted with 15 hospice clinicians (physicians, nurses, pharmacists).
- Interviews were guided by the Theoretical Domains Framework Version 2 (TDFv2) and data were thematically analyzed.
- Deprescribing determinants were mapped to TDFv2 domains, prioritized, and linked to Behavior Change Techniques (BCTs).
Main Results:
- Ten key determinants of deprescribing were identified and mapped to seven TDFv2 domains.
- Key determinants included inconsistent guidance awareness, reliance on clinical judgment, patient emotions (fear, anxiety), need for ethical framing, patient-centered justifications, ethical uncertainty, and system-level gaps.
- The developed framework includes Contextualized Deprescribing (CoDe) with electronic prompts and Ethical Therapeutic Insight for Compassionate Communication (ETHIC-Talk) with communication strategies.
Conclusions:
- The CoDe/ETHIC-Talk Framework offers a structured, context-sensitive approach to hospice deprescribing.
- It aims to integrate clinical support with ethically attuned communication.
- Further feasibility evaluation is pending.
Keywords:
DeprescribingEthical communicationHospice careImplementation frameworkLogic modelQualitative researchMore Related Videos
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