Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

1.3K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

52
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
52
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

785
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
785
Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

1.3K
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
1.3K
Air-entraining Agents01:27

Air-entraining Agents

301
Air-entraining agents improve the durability and workability of concrete in climates with frequent freezing and thawing. These agents prevent cracks by introducing small air bubbles into the mix, creating spaces accommodating water expansion when temperatures drop. The air-entraining agents lower the surface tension of water, forming stable, small air bubbles. This method is more effective than having accidental large voids, as the intentional, smaller, and evenly distributed air voids improve...
301
Sampling Methods: Sample Types01:18

Sampling Methods: Sample Types

3.4K
Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mild traumatic brain injury produces persistent wake-state instability and EEG slowing despite carbon monoxide neuroprotection.

Neurochemistry international·2026
Same author

Traumatic Brain Injury Enhances Susceptibility to Lung Bacterial Infection in Mice and Pigs by Modulating the Innate Immune Response.

Critical care medicine·2026
Same author

Heme Metabolism-Derived Carbon Monoxide Regulates Skeletal Muscle Function.

Journal of cachexia, sarcopenia and muscle·2026
Same author

Healing in a bubble.

Science (New York, N.Y.)·2026
Same author

Inhibiting sirtuin-dependent DNA repair and oxidative stress responses impairs DIPG cell survival.

Research square·2025
Same author

Herbal Combination of <i>Angelica gigas</i>, <i>Zingiber officinale</i>, and <i>Aconitum carmichaeli</i> Alleviates High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice Through NRF2-Mediated Regulation of Adipogenesis and Non-Shivering Thermogenesis.

Food science & nutrition·2025
Same journal

Silicone oil in protein drug products and its implications for formulation stability.

Advanced drug delivery reviews·2026
Same journal

Targeted delivery of proteolysis-targeting chimeras (PROTAC) and molecular glue degraders (MGD).

Advanced drug delivery reviews·2026
Same journal

Lysosome-targeting degrader delivery system: from formulation design to biomedical applications.

Advanced drug delivery reviews·2026
Same journal

Anti-PEG antibodies in nanomedicine: Mechanisms, risks, and opportunities.

Advanced drug delivery reviews·2026
Same journal

Optimizing macrophage-targeted intracellular delivery systems for safe and effective immunotherapies.

Advanced drug delivery reviews·2026
Same journal

Light-controlled CRISPR-dCas9 epigenome editing: advanced drug-delivery strategies and oncology applications.

Advanced drug delivery reviews·2026
See all related articles

Related Experiment Video

Updated: Feb 24, 2026

Preparation and Reactivity of Gasless Nanostructured Energetic Materials
09:50

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Published on: April 2, 2015

10.7K

Gas entrapping materials for damage control.

Paula K N Alves1, Ian C Sutton2, James D Byrne2

  • 1Department of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

Advanced Drug Delivery Reviews
|February 22, 2026
PubMed
Summary
This summary is machine-generated.

Gasotransmitters like nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H₂S) show therapeutic promise. New delivery methods using hydrogels, foams, and solids enhance their clinical application for various diseases.

Keywords:
Carbon monoxideGas deliveryGas entrapping materialsGasotransmittersHydrogen sulfideNitric oxide

More Related Videos

In Situ Gas Analysis and Fire Characterization of Lithium-Ion Cells During Thermal Runaway Using an Environmental Chamber
08:42

In Situ Gas Analysis and Fire Characterization of Lithium-Ion Cells During Thermal Runaway Using an Environmental Chamber

Published on: March 31, 2023

3.2K
Measuring Carbon-based Contaminant Mineralization Using Combined CO2 Flux and Radiocarbon Analyses
11:19

Measuring Carbon-based Contaminant Mineralization Using Combined CO2 Flux and Radiocarbon Analyses

Published on: October 21, 2016

12.4K

Related Experiment Videos

Last Updated: Feb 24, 2026

Preparation and Reactivity of Gasless Nanostructured Energetic Materials
09:50

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Published on: April 2, 2015

10.7K
In Situ Gas Analysis and Fire Characterization of Lithium-Ion Cells During Thermal Runaway Using an Environmental Chamber
08:42

In Situ Gas Analysis and Fire Characterization of Lithium-Ion Cells During Thermal Runaway Using an Environmental Chamber

Published on: March 31, 2023

3.2K
Measuring Carbon-based Contaminant Mineralization Using Combined CO2 Flux and Radiocarbon Analyses
11:19

Measuring Carbon-based Contaminant Mineralization Using Combined CO2 Flux and Radiocarbon Analyses

Published on: October 21, 2016

12.4K

Area of Science:

  • Biochemistry and Pharmacology
  • Translational Medicine
  • Biomaterials Science

Background:

  • Gasotransmitters (nitric oxide, carbon monoxide, hydrogen sulfide) are endogenous signaling molecules regulating vital cellular processes.
  • These gases influence cardiovascular, immune, and nervous system functions, with therapeutic potential in diseases like cancer and sepsis.
  • Challenges exist in safe, targeted delivery of gasotransmitters due to their toxicity at high concentrations.

Purpose of the Study:

  • To review current strategies for delivering gasotransmitters (NO, CO, H₂S).
  • To discuss mechanisms, tissue distribution, and reactivity of gasotransmitters.
  • To highlight the clinical utility and translational relevance of novel delivery approaches.

Main Methods:

  • Review of current literature on gasotransmitter delivery systems.
  • Analysis of hydrogels, foams, and solid formulations for NO, CO, and H₂S delivery.
  • Discussion of preclinical and clinical studies on gasotransmitter administration.

Main Results:

  • Various delivery systems (hydrogels, foams, solids) are being developed for NO, CO, and H₂S.
  • These systems facilitate delivery across skin and gut barriers, exploiting gas diffusion.
  • Optimized administration, dosage, and specificity are crucial for therapeutic efficacy.

Conclusions:

  • Controlled exogenous administration of gasotransmitters offers significant therapeutic potential.
  • Advanced delivery strategies are essential for overcoming challenges in clinical translation.
  • Further research into optimizing delivery methods will enhance the use of gasotransmitters as therapeutic agents.