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Isolation of Genetically Similar Group A Streptococcal Strains From Siblings With Concurrent Invasive Group A

Samuel Showalter1,2, Sam Baird3, Daniel Mallal3

  • 1Department of Pediatric Infectious Disease, Children's Hospital Colorado, Aurora, CO.

The Pediatric Infectious Disease Journal
|February 23, 2026
PubMed
Abstract

No abstract available in PubMed .

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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