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Ultrasonic Assessment of Myocardial Microstructure
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Case Report: Contrast adenosine stress echocardiography revealing microvascular dysfunction in cardiac AL amyloidosis

Yuqian Dai1, Yan Deng2,3, Ni Lin2,3

  • 1Department of Anatomical Sciences, School of Medicine, St. George's University, St. George's, Grenada.

Frontiers in Cardiovascular Medicine
|February 23, 2026
PubMed

Insights

Cardiac amyloidosis (CA) diagnosis is improved by assessing coronary microvascular dysfunction. Contrast adenosine stress echocardiography effectively reveals impaired myocardial perfusion and reduced coronary flow velocity reserve (CFVR) in CA patients.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Medical Diagnostics

Background:

  • Cardiac amyloidosis (CA) is an underdiagnosed cause of restrictive cardiomyopathy.
  • Coronary microvascular dysfunction is a key feature in CA, impacting diagnosis and monitoring.
  • Noninvasive assessment methods are crucial for early detection.

Keywords:
cardiac amyloidosiscase reportcontrast stress echocardiographyinfiltrative cardiomyopathymultiple myeloma

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