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Related Concept Videos

Blood Types02:20

Blood Types

23.3K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
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The ABO Blood Group01:12

The ABO Blood Group

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The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Blood Transfusion01:15

Blood Transfusion

2.5K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Related Experiment Video

Updated: Feb 24, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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ABO Blood Groups as Predictors of Oral Malignancy Risk - A Retrospective Study.

Abhilasha Yadav1,2, Anuj Jain3,4, Rajiv Borle2

  • 1Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Mumbai, Maharashtra, India.

Annals of Maxillofacial Surgery
|February 23, 2026
PubMed
Summary

Individuals with blood group A have a 1.46-fold higher risk of developing oral cancer. This study highlights blood group A as a potential predictive marker for oral malignancies in the Indian population, aiding early detection efforts.

Keywords:
ABO blood grouporal malignancyoral squamous cell carcinomapredictive markerrisk factor

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Area of Science:

  • Oncology
  • Genetics
  • Public Health

Background:

  • Oral cancer is a significant global health concern, particularly in developing nations.
  • Genetic and immunological factors influencing oral cancer risk are not fully understood.
  • Identifying predictive markers is crucial for early detection and prevention strategies.

Purpose of the Study:

  • To investigate the association between ABO blood groups and oral malignancy risk in the Indian population.
  • To explore the potential of ABO blood groups as predictive markers for oral cancer.
  • To provide insights for targeted screening programs and improved patient outcomes.

Main Methods:

  • A retrospective case-control study involving 307 oral malignancy patients and 600 healthy controls.
  • Data collection included demographic details, ABO blood group, and cancer site.
  • Statistical analysis employed the Chi-square test and odds ratios to assess risk association.

Main Results:

  • Blood group A was most prevalent among oral malignancy cases.
  • Individuals with blood group A showed a 1.46-fold increased risk of oral malignancies (P < 0.05).
  • The peak incidence of oral cancer was observed in the fifth decade, with buccal mucosa being the most affected site.

Conclusions:

  • A significant association exists between blood group A and increased oral malignancy risk in the Indian population.
  • Blood group A may serve as a valuable indicator for identifying individuals at higher risk.
  • Findings support the development of targeted screening programs for early oral cancer detection and management.