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Rapid Detection of Nanoplastic Contamination in Plastic Labware by Dynamic Light Scattering Highlights Variations in
Wei Wei1, Song Lin Chua1,2
1Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon 999077, Hong Kong SAR, China.
ACS Measurement Science Au
|February 23, 2026
Summary
Laboratory plastics release nanoplastics (NPs), posing contamination risks. Dynamic light scattering (DLS) offers a rapid method to detect these NPs, crucial for research integrity and environmental safety.
Area of Science:
- Environmental Science
- Analytical Chemistry
- Materials Science
Background:
- Nanoplastics (NPs) are prevalent environmental contaminants with potential health risks.
- Current detection methods (NTA, SEM) for NPs are labor-intensive and challenging.
- There is a critical need for rapid and accessible NP detection techniques.
Purpose of the Study:
- To develop and apply dynamic light scattering (DLS) for rapid quantification of NP concentrations and sizes.
- To identify laboratory plastic consumables as a significant source of nanoplastics.
- To investigate the impact of laboratory procedures on NP release and experimental outcomes.
Main Methods:
- Utilized dynamic light scattering (DLS) for rapid NP quantification.
- Analyzed common laboratory plastic consumables (microcentrifuge tubes, cryovials, Petri dishes).
- Investigated NP release triggered by pipetting, sonication, and liquid nitrogen treatment.
Main Results:
- Demonstrated widespread NP contamination from laboratory plasticware.
- Confirmed that routine lab actions and physical/chemical treatments increase NP release.
- Observed interference of NPs with DNA and iron nanoparticle concentration measurements.
- Identified NPs composed of polystyrene and polypropylene.
Conclusions:
- Laboratory plastic consumables are an under-recognized source of nanoplastic contamination.
- Nanoplastic release compromises research integrity and contributes to environmental pollution.
- Sustainable laboratory practices and contamination control are essential to mitigate NP risks.
