The African measles and rubella laboratory network: 21 years of functioning in West Africa

The WHO (World Health Organization) African Region measles/rubella laboratory network was established to provide support to the measles/rubella elimination program. From the official designation of a laboratory to the provision of basic equipment and training, regular laboratory assessment, the network has been functioning for more than 21 years in a standardized manner. We analyzed the performance of the laboratory network in the Western Africa Subregion. The comparison of the period 2004-2013 versus the period 2014-2024 shows an increase in the average number of functioning laboratories, specimens received /tested and onsite accreditation reviews conducted. The overall timeliness in sending out IgM results to EPI/national level remains above the expected target. Quarterly confirmatory testing for serology is implemented by most of the laboratories. More than 92% of the laboratories have obtained a passing score for annual serology Proficiency Test. With the molecular tests taking place in laboratories that have passed the molecular external quality assurance test, measles B3 genotypes were identified in 11 countries of the sub-Region over the past 21 years. As of today, the measles and rubella laboratory network in West Africa continues to operate despite the various challenges faced.