Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Glaucoma: Overview01:25

Glaucoma: Overview

1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fuzzy multi-criteria selection of sensor architectures for coastal pollution monitoring.

Scientific reports·2026
Same author

Red Blood Cell Exchange Transfusion for Severe Babesiosis.

JAMA internal medicine·2026
Same author

CHARACTERIZING INTRAOCULAR LENS POSITION, STABILITY, AND IRIS MOBILITY IN EYES THAT HAVE UNDERGONE SUTURELESS INTRASCLERAL HAPTIC FIXATION.

Retina (Philadelphia, Pa.)·2026
Same author

POSTENDOPHTHALMITIS "BUCKET HANDLE SIGN" SIGNIFIES BULLOUS INTERNAL LIMITING LAMINA SEPARATION.

Retina (Philadelphia, Pa.)·2026
Same author

COMBINED AMNIOTIC MEMBRANE GRAFT AND AUTOLOGOUS RETINAL TRANSPLANT FOR REPAIR OF REFRACTORY CHRONIC MYOPIC MACULAR HOLES.

Retinal cases & brief reports·2026
Same author

LONG-TERM OUTCOMES AFTER IMPLANTATION OF SUTURELESS INTRASCLERAL FIXATION LENSES AFTER COMPLICATED CATARACT SURGERY - A SINGLE-CENTER RETROSPECTIVE STUDY.

Retina (Philadelphia, Pa.)·2026

Related Experiment Video

Updated: Feb 24, 2026

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
09:03

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice

Published on: November 15, 2019

10.8K

Outer Retinal Optical Coherence Tomography Changes Associated With Intraocular Silicone Oil Administration.

Viren Govindaraju1, Jong Park2, Fanny Huang3

  • 1Associated Retinal Consultants, Royal Oak, MI, USA.

Journal of Vitreoretinal Diseases
|February 23, 2026
PubMed
Summary

Optical coherence tomography (OCT) reveals outer retinal changes during silicone oil tamponade, potentially causing vision loss. Removing the oil often resolves these OCT changes and improves visual acuity (VA), especially in macula-on cases.

Keywords:
optical coherence tomographyretinal detachmentsilicone oil

More Related Videos

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

8.7K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.7K

Related Experiment Videos

Last Updated: Feb 24, 2026

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
09:03

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice

Published on: November 15, 2019

10.8K
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

8.7K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.7K

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Medical Imaging

Background:

  • Silicone oil tamponade is used in retinal detachment repair.
  • Optical coherence tomography (OCT) visualizes retinal structures.
  • Potential vision-impairing complications of silicone oil require investigation.

Purpose of the Study:

  • To characterize OCT changes associated with silicone oil tamponade.
  • To correlate these OCT findings with visual acuity (VA) outcomes.
  • To evaluate the impact of silicone oil removal on OCT changes and VA.

Main Methods:

  • Retrospective cohort study (2015-2023) of patients undergoing vitrectomy with silicone oil for retinal detachment.
  • Analysis of OCT scans and visual acuity measurements before, during, and after silicone oil tamponade.
  • Comparison of outcomes between macula-on and macula-off detachment groups.

Main Results:

  • Outer retinal OCT changes were observed in patients with silicone oil.
  • In macula-on cases, silicone oil removal significantly improved VA (P=.04) and resolved OCT changes in most patients.
  • In macula-off cases, OCT changes resolved, but VA did not significantly improve after oil removal (P=.057).

Conclusions:

  • Silicone oil tamponade can induce outer retinal OCT changes impacting vision.
  • Over 90% of these OCT changes and associated vision loss resolved after silicone oil removal.
  • Prompt silicone oil removal may enhance visual outcomes, particularly if the macula was not detached initially.