Preservation of rat liver tissue by endodontic therapeutic agents

The preservation action of seven endodontic therapeutic agents has been tested on rat liver tissue. Such agents can be divided into three catagories: formaldehyde-containing, parachlorophenol-containing, and miscellaneous compounds. Besides their bactericidal and fungicidal effects, they also have a fixative action on tissue components. Because of this double action, they are called preservatives. In this series of experiments 25 percent formalin in 80 percent ethanol gave the best combination of bactericidal, fungicidal, and fixation properties.