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Correction for Participation Bias in Nonprobability Samples Using Multiple Reference Surveys
Victoria Landsman1,2, Lingxiao Wang3, Ivan Carrillo-Garcia4
1Institute for Work and Health, Toronto, Canada.
Statistics in Medicine
|February 23, 2026
Summary
This study introduces a new framework to reduce bias in health research surveys using multiple reference samples. The proposed calibration estimators improve accuracy when participation mechanisms are unknown.
Area of Science:
- Survey methodology
- Statistical inference
- Health research
Background:
- Nonprobability sampling is increasingly used in health research.
- Participation mechanisms in these samples are often unknown, leading to potential bias in estimates and associations.
- Existing methods for statistical inference from nonprobability samples are limited to a single reference sample.
Purpose of the Study:
- To propose a general framework for addressing participation bias in nonprobability samples using multiple reference surveys.
- To extend current statistical inference capabilities beyond single-reference sample limitations.
- To focus on calibration estimators for practical implementation and flexibility.
Main Methods:
- Developed a general framework accommodating multiple reference surveys.
- Focused on calibration estimators, a flexible special case within the framework.
- Proposed two variance estimation methods: Taylor linearization and leave-one-out jackknife.
Main Results:
- The proposed framework successfully addresses participation bias.
- Raking ratio calibration estimators showed satisfactory performance, especially with dispersed participation probabilities.
- Variance estimates for continuous outcomes were markedly smaller using the proposed methods.
Conclusions:
- The new framework and calibration estimators effectively mitigate bias in nonprobability samples.
- The methods offer practical advantages, particularly with limited microdata access.
- Demonstrated utility in a real-world study of Canadian working adults.
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