Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ChatGPT Versus Custom-Trained Chatbot for Urogynecology Surgery Counseling.

Urogynecology (Philadelphia, Pa.)·2026
Same author

Symptoms and subtypes of patients with lower urinary tract dysfunction - insights from the Symptoms of Lower Urinary Tract Dysfunction Research Network.

Nature reviews. Urology·2026
Same author

Cesarean section rates in Lucas do Rio Verde, Brazil: Assessing the impact of socioeconomic status and maternal and neonatal outcomes.

Women's health (London, England)·2026
Same author

Understanding barriers to pediatric hydrocephalus management: an international survey.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same author

Self-care Pessary Management and Factors Associated With Long-Term Pessary Use.

Urogynecology (Philadelphia, Pa.)·2026
Same author

Renovating the Barnes maze for mouse models of dementia with STARR FIELD: A 4-day protocol for learning rate, retention, and cognitive flexibility.

Methods (San Diego, Calif.)·2026

Related Experiment Video

Updated: Jul 13, 2026

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
03:49

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System

Published on: September 20, 2018

21.2K

Preoperative Gabapentin for Vaginal Prolapse Procedures: A Randomized Trial.

Colin M Johnson1, Kimberly A Kenne, Catherine S Bradley

  • 1Iowa City, IA. Department of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery.

Urogynecology (Philadelphia, Pa.)
|February 23, 2026
PubMed
Summary

Preoperative gabapentin did not reduce opioid use or improve pain control in patients undergoing vaginal prolapse surgery. These findings suggest limited benefit for routine gabapentin use in enhanced recovery after surgery (ERAS) protocols for these procedures.

More Related Videos

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

6.7K
Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

2.6K

Related Experiment Videos

Last Updated: Jul 13, 2026

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
03:49

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System

Published on: September 20, 2018

21.2K
Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

6.7K
Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

2.6K

Area of Science:

  • Gynecologic surgery
  • Anesthesiology
  • Pharmacology

Background:

  • Enhanced Recovery After Surgery (ERAS) protocols often include perioperative gabapentin.
  • Evidence for gabapentin's efficacy in vaginal prolapse procedures is limited.

Purpose of the Study:

  • To evaluate the effect of preoperative gabapentin on postoperative opioid consumption.
  • To assess pain control and recovery outcomes in patients undergoing vaginal apical suspension for pelvic organ prolapse.

Main Methods:

  • A double-blind, randomized, placebo-controlled trial.
  • Participants received gabapentin (300 mg) or placebo 1 hour pre-surgery, with acetaminophen and celecoxib.
  • Primary outcome: 24-hour postoperative opioid use (morphine milligram equivalents).

Main Results:

  • No significant difference in 24-hour opioid use between gabapentin and placebo groups (P=0.15).
  • Secondary outcomes including pain scores and time to discharge were also not significantly different.
  • Regression and per-protocol analyses confirmed these findings.

Conclusions:

  • A single preoperative dose of gabapentin did not reduce opioid use or improve pain control.
  • Gabapentin demonstrated limited utility in this specific surgical context.
  • Findings question the routine use of gabapentin in ERAS protocols for vaginal apical suspension.