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Primary Pseudomyogenic Hemangioendothelioma of the Cranium: Findings on FDG-PET/CT
1Department of Nuclear Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China.
Abstract:
Pseudomyogenic hemangioendothelioma (PMH) is an extremely rare intermediate-grade vascular neoplasm. It often arises in the distal extremities and characteristically involves multiple tissue planes. It has a male predominance, and usually affects individuals in the second to fourth decades of life. Here we report a 54-year-old man who presented with an occipital mass lasting for three months. On imaging studies, the occipital bone tumors were expansile, well circumscribed and lytic, accompanied by adjacent scalp and subcutaneous nodules, with marked enhancement of the lesion upon contrast administration. FDG PET/CT demonstrated high FDG affinity in the lesion. Surgical pathology diagnosed as PMH.
Insights
Pseudomyogenic hemangioendothelioma (PMH) is a rare vascular neoplasm. This case report details a unique occipital bone presentation of PMH in a 54-year-old male, confirmed by surgical pathology.
Area of Science:
- Oncology
- Vascular Neoplasms
- Pathology
Background:
- Pseudomyogenic hemangioendothelioma (PMH) is an extremely rare intermediate-grade vascular neoplasm.
- It typically affects the distal extremities and occurs in younger individuals.
- This neoplasm has a male predominance.
Purpose of the Study:
- To report an unusual case of PMH presenting as an occipital mass.
- To describe the imaging and pathological findings of this rare presentation.
Main Methods:
- Case report of a 54-year-old male with an occipital mass.
- Imaging studies including contrast-enhanced CT and FDG PET/CT were performed.
- Diagnosis was confirmed by surgical pathology.
Main Results:
- The occipital mass was expansile, well-circumscribed, and lytic, with adjacent scalp and subcutaneous nodules.
- Imaging showed marked enhancement and high FDG uptake.
- Surgical pathology confirmed the diagnosis of PMH.
Conclusions:
- PMH can present atypically, including in the skull.
- Multimodality imaging is crucial for characterizing PMH.
- Surgical pathology remains the gold standard for diagnosis.
