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Published on: November 16, 2011
Glucocorticoid Therapy and Miglitol Ameliorate Reactive Hypoglycemia Secondary to Late Dumping Syndrome
Manabu Saito1, Hiroshi Uchino1, Arisa Yoshida1
1Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Toho University Graduate School of Medicine, Japan.
Abstract:
We report a case in which low-dose prednisolone (LD-PSL) and an absorbable α-glucosidase inhibitor (miglitol) effectively treated reactive hypoglycemia caused by late dumping syndrome. A 73-year-old man underwent gastric tube reconstruction after an esophagectomy for esophageal cancer. Frequent diet management and a non-absorbable α-glucosidase inhibitor (voglibose) were prescribed to treat the reactive hypoglycemia caused by late dumping syndrome; however, hypoglycemia persisted. Changing the treatment to LD-PSL and miglitol ameliorated the reactive hypoglycemia and led to a resolution of hypoglycemic symptoms. Treatment with LD-PSL and miglitol is an effective treatment option for late dumping syndrome which does not respond to either guideline-based dietary modifications or voglibose treatment.
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