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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Computed Tomography Derived Procedure Simulations for Redo Transcatheter Aortic Valve Replacement.

Mark M P van den Dorpel1, Ole de Backer2, Mohamed Abdel-Wahab3

  • 1Cardiovascular Institute, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|February 24, 2026
PubMed
Summary
This summary is machine-generated.

Redo transcatheter aortic valve replacement (redo-TAVR) simulations using FEops HEARTguide software accurately predict coronary accessibility and valve expansion. This pilot study validates the software

Keywords:
coronary accessibilityprosthesis‐patient mismatchredo‐TAVRsimulation

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Area of Science:

  • Cardiovascular Imaging and Interventions
  • Computational Modeling in Medicine
  • Prosthetic Valve Performance Analysis

Background:

  • Transcatheter aortic valve (TAV) failure necessitates redo-TAVR, posing risks like compromised coronary artery access and prosthesis-patient mismatch due to multiple valve layers.
  • Multi-slice computed tomography (MSCT) imaging combined with dedicated software offers potential for simulating TAV deployment to predict outcomes.
  • Accurate simulation is crucial for planning redo-TAVR procedures and mitigating potential complications.

Purpose of the Study:

  • To validate the accuracy of redo-TAVR simulations generated by FEops HEARTguide software.
  • To assess the software's ability to predict key procedural and anatomical outcomes in redo-TAVR patients.

Main Methods:

  • A multicenter observational study included 25 patients undergoing redo-TAVR with available baseline, post-index-TAVR, and post-redo-TAVR MSCT imaging.
  • Patient-specific redo-TAVR simulations were created using FEops HEARTguide software.
  • Simulated outcomes including valve-to-coronary (VTC) distance, neoskirt height, TAV expansion, and residual valve area were compared against follow-up MSCT data.

Main Results:

  • Simulations demonstrated good agreement with follow-up MSCT for VTC distance (ICC > 0.740) and TAV frame expansion (ICC > 0.822).
  • Moderate agreement was observed for valve-to-sinotubular-junction (VTSTJ) distance (ICC > 0.613).
  • Simulations of residual valve area showed good agreement for both self-expanding and balloon-expandable TAVs (ICC > 0.823).

Conclusions:

  • MSCT-derived simulations using FEops HEARTguide provide accurate insights into coronary accessibility, TAV expansion, and residual valve area in redo-TAVR.
  • These findings support the potential utility of simulation software in planning and optimizing redo-TAVR procedures.